Cookies are used by this site. SCSA, sperm chromatin structure assay. By continuing to use this site, you are agreeing to their use. In the opposite, no correlation was found between sperm morphology and sperm condensation evaluated by AB test in other studies [ 14 ]. It is a completely independent variable. Introduction In Western countries, up to one-fourth of couples in reproductive age are seeking medical help for involuntary childlessness. The resulting embryos may then be placed into the uterus of the female to establish a pregnancy.
Male Fertility Tests & Procedures
J Assist Reprod Genet. DNA strand breaks in human spermatozoa: The shape of your sperm morphology is also important since sperm that are shaped incorrectly have a have a harder time fertilizing eggs. Sperm chromatin structure and male fertility: Combining SCSA analysis with assessment of traditional sperm parameters, gives a higher precision in the prediction of fertility.
Sperm Chromatin Structure Assay & DNA Fragmentation
Similarly, Razavi et al. Even among men with low sperm concentration, poor motility or morphology, there will be men with a certain potential of fertility. According to some literature data [ 14 , 22 , 23 ], our study demonstrated that there is no correlation between the degree of sperm chromatin condensation assessed by AB staining and some sperm parameters, including motility, vitality, and sperm count. Excellent to Good fertility potential 15 percent to 25 percent DFI: If your white blood cell count is higher, we may take a semen culture to diagnose and treat the problem. Certain cancer treatments involving chemotherapy and radiation therapy are known to adversely affect male fertility. The mechanism that probably, for which most evidence exists, is the OS caused by an imbalance between the antioxidant ability in seminal plasma and the production of ROS, leading to the formation of oxidative products such as 8OHdG.
Some common examles are certain forms of severe arthritis, lupus, diabetes, and in reproduction, premature menopause ovarian failure and antisperm antibodies. Dear Rachel please have your husband tested. Moreover, the chromatin of sperm with reduced amounts of protamines was observed to be susceptible to chemical disruption [ 63 ]. More recently, Zini et al. However, the rates of some morphology abnormalities were higher in G2: